The physio-pathological abnormalities, which distinguish a patient with ME from other diseases
Is it possible to diagnose ME/CFS ? (Source : ME/cvs Vereniging Nederland, www.me-cvsvereniging.nl ) This is such an important presentation - to show to anyone who doubts that ME is real ! Professor K. De Meirleir succiently outlines some of the physio-pathological abnormalities – which distinguish a patient with ME from other diseases : Dysfunctional immune system - chronic infections which hardly ever occur in normal people . Underlying intestine disorders– dysbiosis, gut permeability. Problems of oxidative stress leading to DNA impairment, impaired proteins and structures . Faulty mitochondria – shortage of oxygen and energy supply in body. Cardiac abnormalities, heat defects, heart not being filled completely, too little blood volume, poor blood circulation . Exercise capacity very important – in early stages little reduction in exercise capacity, but as years progress exercise capacity decreases quickly- much faster than in normal ageing. Diaphragm sta